PM's |
Prasenjit Mondal, PhD
Postdoctoral Research Scholar at Department of Neurology, Massachusetts General Hospital,
Harvard Medical School, USA
Before you know you must imagine.. Nobel Laureate Richard Axel
Patents:
6. An Easy-To-Use Diagnostic System For Rapid Dengue Virus Detection Using Fluorescence-Based Molecular probe. S. Biswas, S. Ghosh, S. Sukla, P. Mondal, Indian Pat. Appl. (2020), IN 202011019066.
5. Pharmaceutical compositions comprising nonapeptide. S. Ghosh, P. Mondal, G. Das, J. Khan, K. Pradhan, PCT Int. Appl. (2019), WO 2019229771 A2 20191205.
4. Prepn. of peptoid pharmaceutical compns. for treatment of Alzheimer's disease. S. Ghosh, K. Pradhan, G. Das, P. Mondal, S. Barman, S. Ghosh, PCT Int. Appl. (2019), WO 2019211878 A1 20191107.
3. “Nonapeptide of formula I, pharmaceutical compositions and methods for preparation thereof” By S. Ghosh, P. Mondal, G. Das, J. Khan, K. Pradhan, Indian Pat. Appl. (2018), IN 201811020565.
2. “Peptoid of formula I, pharmaceutical compositions and method for preparation thereof.” By S. Ghosh, K. Pradhan, G. Das, P. Mondal, S. Barman, S. Ghosh, Indian Pat. Appl. (2018), IN 201811016874.
1. “A hexapeptide interacts with tubulin/microtubule and exhibits significant neuroprotection against Aβ toxicity thereof” by S. Ghosh, A. Biswas, B. Jana, S. Mohapatra, S. C. Biswas, S. Saleem, P. Mondal, A. Adak, S. Ghosh, A. Saha, D. Bhunia. US patent Filed (CSIR Ref. No. 0210NF2015).
Publications:
2024
40. Megan E Bosch, Hemraj B Dodiya, Julia Michalkiewicz, Choonghee Lee, Shabana M Shaik, Ian Q Weigle, Can Zhang, Jack Osborn, Aishwarya Nambiar, Priyam Patel, Samira Parhizkar, Xiaoqiong Zhang, Marie L Laury, Prasenjit Mondal, Ashley Gomm, Matthew John Schipma, Dania Mallah, Oleg Butovsky, Eugene B Chang, Rudolph E Tanzi, Jack A Gilbert, David M Holtzman, Sangram S Sisodia Sodium oligomannate alters gut microbiota, reduces cerebral amyloidosis and reactive microglia in a sex-specific manner. Molecular Neurodegeneration, 2024, 19(1), 18. [IF 18.8][Link]
39. Prasenjit Mondal, Ping Bai, Ashley Gomm, Grisilda Bakiasi, Chih-Chung Jerry Lin, Yanli Wang, Se Hoon Choi, Rudolph E. Tanzi, Changning Wang,* Can Zhang.* Structure-based discovery of a small molecule inhibitor of histone deacetylase 6 (HDAC6) that significantly reduces alzheimer's disease neuropathology. Advanced Science, 2024, 11(1), 2304545. [IF 15.1][Link]
38. Nabanita Mukherjee, Debmalya Bhunia, Prabir Kumar Garai, Prasenjit Mondal, Surajit Barman, and Surajit Ghosh.* Designed Novel Nuclear Localizing Anticancer Peptide Targets p53 Negative Regulator MDM2 Protein. Journal of Peptide Science, 2024, 30(1), e3535 [IF 2.4][Link]
2023
37. Ping Bai, Yan Liu, Liuyue Yang, Weihua Ding, Prasenjit Mondal, Na Sang, Gang Liu, Xiaoxia Lu, Thanh Tu Ho, Yanting Zhou, Rui Wu, Vishal C. Birar, Moses Q. Wilks, Rudolph E. Tanzi, Hening Lin, Can Zhang, Weimin Li*, Shiqian Shen*, Changning Wang.* Development and Pharmacochemical Characterization Discover a Novel Brain-Permeable HDAC11-Selective Inhibitor with Therapeutic Potential by Regulating Neuroinflammation in Mice, Journal of Medicinal Chemistry, 2023, 66(23), 16075-16090. [IF 8.039][Link]
36. Shi Kuang, Biyue Zhu, Jing Zhang, Fan Yang, Bo Wu, Weihua Ding, Liuyue Yang, Shiqian Shen, Seven H. Liang, Prasenjit Mondal, Mohanraja Kumar, Rudolph E. Tanzi, Can Zhang, Hui Chao, Chongzhao Ran.* A Photolabile Curcumin-Diazirine Analogue Enables Phototherapy with Physically and Molecularly Produced Light for Alzheimer's Disease Treatment. Angewandte Chemie, 2023, 135 (45), e202312519 [IF 16.6][Link]
35. Gang Liu, Prasenjit Mondal, Na Sang, Zihua Li, Weihua Ding, Liuyue Yang, Yan Liu, Vishal C Birar, Rudolph E Tanzi, Can Zhang, Shiqian Shen, Changning Wang, Xiaoxia Lu, Ping Bai.* and Surajit Ghosh.* Design, synthesis, and anti-inflammatory activity characterization of novel brain-permeable HDAC6 inhibitors. European Journal of Medicinal Chemistry, 2023, 254, 115327. [IF 7.1][Link]
2022
34. Anindyasundar Adak, Gaurav Das, Varsha Gupta, Juhee Khan, Nabanita Mukherjee, Prasenjit Mondal, Rajsekhar Roy, Surajit Barman, Prabir Kumar Gharai, Surajit Ghosh.* Evolution of Potential Antimitotic Stapled Peptides from Multiple Helical Peptide Stretches of the Tubulin Heterodimer Interface: Helix-Mimicking Stapled Peptide Tubulin Inhibitors. Journal of Medicinal Chemistry, 2022, 65 (20), 13866-13878. [IF 8.039][Link]
33. Ping Bai, Prasenjit Mondal, Frederick A Bagdasarian, Nisha Rani, Yan Liu, Ashley Gomm, Darcy R Tocci, Se Hoon Choi, Hsiao-Ying Wey, Rudolph E Tanzi, Can Zhang, Changning Wang.* Development of a potential PET probe for HDAC6 imaging in Alzheimer's disease. Acta Pharmaceutica Sinica B, 2022, 12 (10), 3819-3904. [IF 14.9][Link]
32. Shivanshu Mishra, Pharyanshu Kachhawa, Prasenjit Mondal, Surajit Ghosh, Chaturvedula Tripura, Nidhi Chaturvedi.* AlGaN/GaN HEMT Based Biosensor for Detection of the HER2 Antigen Spiked in Human Serum. IEEE Transactions on Electron Devices, 2022, 69 (8), 4527-4533. [IF 3.2][Link]
31. Prasenjit Mondal, Saswat Mohapatra, Debmalya Bhunia, Prabir Kumar Gharai, Nabanita Mukherjee, Varsha Gupta, Satyajit Ghosh, Surajit Ghosh.* Designed hybrid anticancer nuclear-localized peptide inhibits aggressive cancer cell proliferation. RSC Medicinal Chemistry, 2022, 13 (2), 196-201. [IF 4.31][Link]
2021
30. Soumi Sukla, Prasenjit Mondal, Subhajit Biswas, Surajit Ghosh.* A Rapid and Easy-to-Perform Method of Nucleic-Acid Based Dengue Virus Diagnosis Using Fluorescence-Based Molecular Beacons. Biosensors, 2021, 11 (12), 479. [IF 5.473][Link]
29. Saswat Mohapatra, Varsha Gupta, Prasenjit Mondal, Shreyam Chatterjee, Debmalya Bhunia, Surajit Ghosh.* A Small Molecule with Bridged Carbonyl and Tri‐fluoro‐aceto‐phenone Groups Impedes Microtubule Dynamics and Subsequently Triggers Cancer Cell Apoptosis. ChemMedChem, 2021, 16 (17), 2703-2714. [IF 3.5][Link]
28. Saswat Mohapatra, Gaurav Das, Varsha Gupta, Prasenjit Mondal, Masashi Nitani, Yutaka Ie, Shreyam Chatterjee, Yoshio Aso, Surajit Ghosh* Power of an organic electron acceptor in modulation of intracellular mitochondrial reactive oxygen species: Inducing JNK-and caspase-dependent apoptosis of cancer cells. ACS omega, 2021, 6 (11), 7815-7828. [IF 4.13][Link]
2019
27. Prasenjit Mondal, Rajdeep Chowdhury, Somen Nandi, Md Asif Amin, Kankan Bhattacharyya* and Surajit Ghosh.* Probing Deviation of Adhered Membrane Dynamics between Reconstituted Liposome and Cellular System. Chemistry-An Asian Journal, 2019, 14 (24), 4616-4624. [IF 4.56][Link]
26. Prasenjit Mondal, Juhee Khan, Varsha Gupta and Surajit Ghosh.* In silico Approach for Designing Potent Neuroprotective Hexapeptide. ACS Chem Neurosci. 2019, 10 (6), 3018-3030. [IF 5.78][Link]
25. Surajit Barman, Gaurav Das, Varsha Gupta, Prasenjit Mondal, Krishnangsu Pradhan, Batakrishna Jana, Debmalya Bhunia, Juhee Khan, Deepshikha Mukherjee and Surajit Ghosh.* Dual Arm Nanocapsule Targets Neuropilin-1 Receptor and Microtubule: A Potential Nanomedicine Platform. Mol. Pharmaceutics 2019, 16 (6), 2522-2531. [IF 4.396][Link]
24. Prasenjit Mondal, Gaurav Das, Juhee Khan, Krishnangsu Pradhan, Rathnam Mallesh, Abhijit Saha, Batakrishna Jana, and Surajit Ghosh*, Potential Neuroprotective Peptide Emerged from Dual Neurotherapeutic Targets: A Fusion Approach for the Development of anti-Alzheimer’s Lead, ACS Chem. Neurosci., 2019, 10 (5), 2609-2620. [IF 4.9][Link]
23. Surajit Barman, Gaurav Das, Prasenjit Mondal, Krishnangsu Pradhan, Batakrishna Jana, Debmalya Bhunia, Abhijit Saha, Chirantan Kar, and Surajit Ghosh.* Tripodal Molecular Propeller Perturbs Microtubule Dynamics: Indole acts as a Blade and Plays Crucial Role in Anticancer Activity. Chem. Commun., 2019, 55, 2356-2359. [IF 6.8][Link]
22. Tanushree Mahata#, Prasenjit Mondal#, Debmalya Bhunia, Somen Nandi, Prashant Kurkute, Kankan Bhattacharyya* and Surajit Ghosh.* Self-assembly of Antimitotic Peptide at Membranes: Computational and Experimental Investigation. ACS Omega 2019, 4 (1), 745-754. [IF 4.13][Link]
21. Surajit Barman, Gaurav Das, Prasenjit Mondal, Krishnangsu Pradhan, Debmalya Bhunia, Juhee Khan, Chirantan Kar, and Surajit Ghosh.* Power of Tyrosine Assembly in Microtubule Stabilization and Neuroprotection Fuelled by Phenol Appendages. ACS Chem Neurosci. 2018, 10 (3), 1506-1516. [IF 5.78][Link]
20. Krishnangsu Pradhan, Gaurav Das, Varsha Gupta, Prasenjit Mondal, Surajit Barman, Juhee Khan, Surajit Ghosh.* Discovery of Neuro-regenerative Peptoid from Amphibian Neuropeptide Inhibits Aβ Toxicity and Crossed Blood-Brain Barrier. ACS Chem Neurosci. 2019, 10 (3), 1355-1368. [IF 5.78][Link]
2018
19. Debmalya Bhunia, Krishnangsu Pradhan, Gaurav Das, Subhajit Ghosh, Prasenjit Mondal, Surajit Ghosh.* Matrix metalloproteinase targeted peptide vesicles for delivering anticancer drugs. Chem. Commun., 2018, 54 (67), 9309-9312. [IF 6.8][Link]
18. Krishnangsu Pradhan, Gaurav Das, Prasenjit Mondal, Juhee Khan, Surajit Barman, Surajit Ghosh.* Genesis of Neuroprotective Peptoid from Aβ30-34 Inhibits Aβ Aggregation and AChE Activity, ACS Chem Neurosci. 2018, 9 (12), 2929-2940. [IF 5.78][Link]
17. Prasenjit Mondal, Varsha Gupta, Gaurav Das, Krishnangsu Pradhan, Juhee Khan, Prabir Kumar Gharai, and Surajit Ghosh*, Peptide-based Acetylcholinesterase Inhibitor Crosses Blood-Brain Barrier and Promotes Neuroprotection, ACS Chem. Neurosci., 2018, 9 (11), 2838-2848. [IF 5.78][Link]
16. Debmalya Bhunia,# Prasenjit Mondal,# Gaurav Das, Abhijit Saha, Pallabi Sengupta, Jagannath Jana, Saswat Mohapatra, Subhrangsu Chatterjee, and Surajit Ghosh*, Spatial Position Regulates Power of Tryptophan: Discovery of Major Groove Specific Nuclear Localizing Cell Penetrating Tetrapeptide, J Am Chem Soc., 2018, 140, 1697-1714. [IF 16.38][Link]
15. Gaurav Das, Shyamtanu Chattoraj, Somen Nandi, Prasenjit Mondal, Abhijit Saha, Kankan Bhattacharyya and Surajit Ghosh*. Probing Conformational Dynamics of Photosystem I in Unconfined and Confined Space, Phys Chem Chem Phys., 2018, 20, 449-455. [IF 3.9][Link]
14. Batakrishna Jana#, Prasenjit Mondal#, Abhijit Saha, Anindyasundar Adak, Gaurav Das, Saswat Mohapatra, Prashant Kurkute, and Surajit Ghosh*. Designed Tetrapeptide Interacts with Tubulin and Microtubule. Langmuir, 2018, 34, 1123-1132. [IF 4.33][Link]
13. Prasenjit Mondal, Gaurav Das, Juhee Khan, Krishnangsu Pradhan and Surajit Ghosh*. Crafting of Neuroprotective Octapeptide from Taxol-binding Pocket of β-Tubulin, ACS Chem. Neurosci., 2018, 9, 615–625. [IF 5.78] [Link]
2017
12. Parag Savla#, Gaurav Das#, Prasenjit Mondal#, Rahul Laxman Gajbhiye, Parasuraman Jaisankar, Surajit Ghosh*. Methanolic Extract of Papaya Leaves Shows Neuroprotective Effect. Chemistry Select, 2017, 2, 9454– 9457.[IF 2.3][Link]
11. Asif Amin, Somen Nandi, Prasenjit Mondal, Tanushree Mahata, Surajit Ghosh*, and Kankan Bhattacharyya*. Physical Chemistry in a Single Live Cell: Confocal Microscopy. Phys Chem Chem Phys., 2017, 19, 12620-12627. [IF 3.9][Link]
10. Saswat Mohapatra, Abhijit Saha, Prasenjit Mondal, Batakrishna Jana, Subhajit Ghosh, Atanu Biswas and Surajit Ghosh*. Synergistic anticancer effect of peptide-docetaxel nano-assembly targeted to tubulin: Towards development of dual warhead containing nanomedicine. Adv Healthcare Mater., 2017, 6, 1600718. Accepted as a Back Cover page.[IF 11.09] [Link]
2016
9. Somen Nandi#, Prasenjit Mondal#, Rajdeep Chowdhury#, Abhijit Saha, Surajit Ghosh* and Kankan Bhattacharyya*. Amyloid Beta Peptide inside a Reconstituted Cell-like Liposomal System: Aggregation, FRET, Fluorescence Oscillations and Solvation Dynamics. Phys Chem Chem Phys., 2016, 18, 30444-30451. [IF 3.9] [Link]
8. Debmalya Bhunia#, Saswat Mohapatra#, Prashant Kurkute, Subhajit Ghosh, Batakrishna Jana, Prasenjit Mondal, Abhijit Saha, Gaurav Das and Surajit Ghosh*. Novel Tubulin-targeted Cell Penetrating Antimitotic Octapeptide. Chem. Commun., 2016, 52, 12657-12660. [IF 6.8][Link]
7. Batakrishna Jana, Saswat Mohapatra, Prasenjit Mondal, Surajit Barman, Krishnangsu Pradhan, Abhijit Saha and Surajit Ghosh*. α-Cyclodextrin Interacts Close to Vinblastine Site of Tubulin and Delivers Curcumin Preferentially to the Tubulin Surface of Cancer Cell. ACS Appl. Mater. Interfaces,2016, 8, 13793–13803. [IF 10.38][Link]
6. Anindyasundar Adak#, Saswat Mohapatra#, Prasenjit Mondal, Batakrishna Jana and Surajit Ghosh.* Design of novel microtubule-targeted peptide vesicle for delivering different anticancer drugs. Chem. Commun., 2016, 52, 7549-7552 and Accepted as Cover page. [IF 6.8][Link]
2015
5. Abhijit Saha#, Saswat Mohapatra#, Prashant Kurkute, Batakrishna Jana, Jayita Sarkar, Prasenjit Mondal and Surajit Ghosh*. Targeted delivery of novel peptide-docetaxel conjugate to MCF-7 cell through Neuropilin-1 receptor: Reduced toxicity and enhanced efficacy of docetaxel. RSC Adv., 2015, 5, 92596-92601. [IF 4.03] [Link]
4. Atanu Biswas, Prashant Kurkute, Suraiya Saleem, Batakrishna Jana, Saswat Mohapatra, Prasenjit Mondal, Anindyasundar Adak, Subhajit Ghosh, Abhijit Saha, Debmalya Bhunia, Subhash Chandra Biswas, and Surajit Ghosh*. Novel Hexapeptide Interacts with Tubulin and Microtubules, Inhibits Aβ Fibrillation, and Shows Significant Neuroprotection. ACS Chem. Neurosci., 2015, 6, 1309–1316. (Highlighted in Cover-page) [IF 5.78] [Link]
3. Batakrishna Jana, Jayita Sarkar, Prasenjit Mondal, Surajit Barman, Saswat Mohapatra, Debmalya Bhunia, Krishnangsu Pradhan, Abhijit Saha, Anindyasundar Adak, Subhajit Ghosh and Surajit Ghosh*. A short GC rich DNA derived from microbial origin targets tubulin/microtubule and induces apoptotic death of cancer cell. Chem.Commun. 2015, [IF 6.8][Link]
2. Prasenjit Mondal#, Shyamtanu Chattoraj#, Rajdeep Chowdhury#, Debmalya Bhunia, Surajit Ghosh* and Kankan Bhattacharyya*. Direct observation of the growth and shrinkage of microtubules by single molecule Forster resonance energy transfer†. Phys Chem Chem Phys., 2015, 17, 6687 [IF 3.9][Link]
1. Abhijit Saha, Saswat Mohapatra, Prashant Kurkute, Batakrishna Jana, Prasenjit Mondal, Debmalya Bhunia, Subhajit Ghosh and Surajit Ghosh*Interaction of Aβ peptide with tubulin causes inhibition of tubulin polymerization and apoptotic death of cancer cells. Chem. Commun. 2015, 51, 2249-2252. (Highlighted in Cover-page) [IF 6.8][Link]
# These authors have contributed equally